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Anti-BPDE Monoclonal Antibodies

Polycyclic aromatic hydrocarbons (PAHs) are released into the environment following incomplete combustion of organic materials. Human exposure to PAHs comes from various occupational, environmental, dietary and medicinal sources. Exposure to this group of compounds is believed to be carcinogenic. The most common sources of PAHs are from smoking and from consuming broiled or grilled foods.

Anti-BPDE 8E11
Catalog #: 4360-MC-100
 
Immunogen: The antibody was raised against BPDE-I-G coupled to BSA.
 
Source: Mouse
 
Specificity: The antibody 8E11 recognizes both free PAHs and DNA adducts. In an inhibition assay, the binding of the antibody to BPDE adducts was inhibited by BPDE-I-DNA, BPDE-I-dG, and BPDE-I tetraol but not by BPDE-II-DNA.
 
Subtype: IgG1/k
 
Preparation: The antibody 8E11 is purified from mouse ascites, and provided in PBS containing 0.01% sodium azide.
 
Applications:
  • ELISA
  • Affinity chromotography
  •  
    Anti-BPDE-DNA 5D11
    Catalog #: 4365-MC-100
     
    Immunogen: The antibody was raised against BPDE-I-DNA. The antibody 5D11 is purified from mouse ascites, and provided in PBS containing 0.01% sodium azide.
     
    Source: Mouse
     
    Specificity: The antibody 5D11 recognizes only PAH-DNA (BPDE-I-DNA). The binding of the antibody is inhibited by BPDE-I-DNA, weakly by BPDE-II-DNA and BPDE-I-dG but not by BPDE-I tetraol.
     
    Subtype: IgG2/k
     
    Preparation: The antibody 5D11 is purified from mouse ascites, and provided in PBS containing 0.01% sodium azide.
     
    Applications:
  • ELISA
  • Affinity chromotography
  •  
    Storage: Stored at 4°C. For long term storage, freeze in working aliquots at -20°C in a manual defrost freezer to avoid repeated freeze-thawings.
     
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    Ordering Information
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    Catalog #: Price:

    4360-MC-100
    Anti-BPDE Monoclonal Antibody (Clone 8E11),
    100 µg
    $340.00
    Add to Cart

    4365-MC-100
    Anti-BPDE-DNA Monoclonal Antibody (Clone 5D11),
    100 µg
    $340.00
    Add to Cart

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