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Anti-Human Rad1 Monoclonal Antibody (clone 33)

Cell cycle checkpoints in yeast and humans are activated by DNA damage. Rad1 was identified in yeast as a component of the checkpoint complex using checkpoint mutants. The human homolog of Rad1 has been shown to form a stable radioresponsive checkpoint complex with the human Rad9 and Hus1 proteins. This 32 kDa complex is present in undamaged cells but undergoes extensive modification in response to DNA damage. Human Rad1 exhibits homology with the Ustilago maydis Rec1 exonuclease and may possess a 3’- 5’ exonuclease activity.

Immunogen: Full length recombinant human Rad1.
 
Source: Mouse
 
Specificity: This antibody recognizes mouse and human Rad1.
 
IsoType: IgG2aκ
 
Applications:
  • Western blotting
  •  
    Preparation: This antibody is provided as purified immunoglobulin from mouse ascites in PBS containing 0.01% sodium azide.
     
    Storage: Freeze in working aliquots at -20°C in a manual defrost freezer to avoid repeated freeze-thawings.
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    Ordering Information
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    Catalog #: Price:

    4451-MC-200
    Anti-RAD1 (Clone 33) Monoclonal Antibody,
    200 µg
    $340.00
    Add to Cart

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    TREVIGEN INC. :: 8405 HELGERMAN CT. :: GAITHERSBURG, MD 20877
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