Shopping Cart » DIVAATM     » Cell Invasion     » PathClear® BME     » PARP     » CometAssayTM     » HT 8-oxo-dG ELISA  Home » DNA Damage DNA Damage Anti-Human XPF Antibody Mammalian XPF, a 110 kDa protein, and ERCC1 form a heterodimeric structure-specific DNA nuclease that functions in the nucleotide excision repair (NER) pathway. ERCC1-XPF cleaves a damaged DNA strand on the 5’ side of an opened “bubble” intermediate formed around the lesion. In addition, ERCC1-XPF appears to play a role in repair of interstrand DNA cross-link repair and has recently been demonstrated to cleave DNA on both sides of a psoralen cross-link. Immunogen: Full length recombinant human XPF.   Source: Mouse   Specificity: Anti-XPF (clone 218) recognizes full length human XPF and specifically binds in the c-terminus region (amino acids 854-916). This antibody will not recognize proteolytic degradation fragments.   IsoType: IgG2ak   Applications: Western blotting   Preparation: This antibody is provided as purified immunoglobulin from mouse ascites in PBS containing 0.01% sodium azide.   Storage: Store at 4°C. For long term storage, freeze in working aliquots at -20°C in a manual defrost freezer to avoid repeated freeze-thawings. Top   Ordering Information Catalog #: Price: 4431-MC-100 Anti-XPF (218), 100 µg $340.00 Trevigen Products are now available for ordering through Download Protocol Related Products Anti-Phosphorylated Histone H2AX (gamma-H2AX) Polyclonal Antibod UVssDNA Antibody XRCC1 TREVIGEN INC. :: 8405 HELGERMAN CT. :: GAITHERSBURG, MD 20877 1.800.TREVIGEN :: 1.800.873.8443 :: (FAX) 1.301.560.4973 :: INFO@TREVIGEN.COM