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Anti-PAR Polymer Monoclonal Antibody (clone 10HA)

Poly (ADP-ribose) polymerase (PARP) converts NAD into nicotinamide and polymers of ADP-ribose at glutamic acid residues of nuclear proteins. The majority of polymer chains are linked to PARP itself through automodification. Poly(ADP-ribosyl)ation of subsets of nuclear proteins plays an important role in cell DNA repair, proliferation, replication, recombination, and apoptosis.

Immunogen: The antibody was raised against purified PAR polymer chains of 2 to 50 units long.
 
Source: Mouse
 
Specificity: The antibody is specific for poly (ADP-ribose) polymers and does not recognize structurally related RNA, DNA, ADP-ribose monomers, NAD or other nucleic acid monomers.
 
Subtype: IgG3a
 
Applications:
  • Western blotting
  • ELISA
  • Immunohistochemistry
  • Immunocytochemistry
  •  
    Preparation: The antibody is purified from ascites fluid and stored in unpreserved PBS buffer. The antibody's range of use is at dilutions of 1:500 to 1:2,000.
     
    Storage: Freeze in working aliquots at -20 C or -80 C in a manual defrost freezer to avoid repeated freeze-thawing.
     
    Control: PAR-PARP protein (Cat# 4500-10-P) is included.
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    Ordering Information
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    Catalog #: Price:

    4335-MC-100
    Anti-PAR Monoclonal Antibody,
    100 µl
    $260.00
    Add to Cart

    4335-MC-1K
    Anti-PAR Monoclonal Antibody,
    1000 µl
    $2205.00
    Add to Cart

    4500-10-P
    PARP Treated Protein Control for Western Blot,
    10 µl
    $75.00
    Add to Cart

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    TREVIGEN INC. :: 8405 HELGERMAN CT. :: GAITHERSBURG, MD 20877
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