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Anti-UVssDNA Monoclonal Antibody (clone C3B6)

DNA exposed to UV light accumulates a number of DNA photoproducts, predominantly (6-4) photoproducts and cyclobutane pyrimidine dimers. Isolated DNA may be immobilized in 96 well microplates for analysis by ELISA. Intact cells or tissues may also be investigated using fluorescent immunohistochemical methods. The antibody is ideal for studies involving UV damage to skin or UV damage DNA repair mechanisms.

Immunogen: The antibody was raised against UV irradiated calf thymus ssDNA conjugated to methylated BSA (mBSA) and UV irradiated poly dT-mBSA complex.
 
Source: Mouse
 
Specificity: The anti-UVssDNA antibody recognizes (6-4) dipyrimidine photoproducts in single-stranded DNA (prepared by denaturing isolated DNA). The antibody can detect (6-4) photoproducts in sequences as short as 4 base pairs.
 
Preparation: The antibody is provided as purified ascites containing 0.01% BSA.
 
Applications:
  • ELISA
  • Indirect in situ immunofluorescence
  • CometAssayTM
  •  
    Storage: Stored at 4°C. For long term storage, freeze in working aliquots at -20°C in a manual defrost freezer to avoid repeated freeze-thawings.
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    Ordering Information
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    Catalog #: Price:

    4350-MC-100
    Anti-UVssDNA Monoclonal Antibody,
    100 µg
    $340.00
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    TREVIGEN INC. :: 8405 HELGERMAN CT. :: GAITHERSBURG, MD 20877
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